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Olmesartan Medoxomil+hydrochlorothiazide

About Olmesartan Medoxomil+hydrochlorothiazide

Hydrochlorothiazide+olmesartan Medoxomil belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Hydrochlorothiazide+olmesartan Medoxomil is a combination of two medicines: Olmesartan medoximil and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). It is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Hydrochlorothiazide+olmesartan Medoxomil lowers the fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

You can take Hydrochlorothiazide+olmesartan Medoxomil with food or without food with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, dizziness, and decreased blood pressure. Most of these side effects of Hydrochlorothiazide+olmesartan Medoxomil do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Hydrochlorothiazide+olmesartan Medoxomil can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark colour urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor.

Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, or heart disease or are diabetic. If you are pregnant or breastfeeding, do not take Hydrochlorothiazide+olmesartan Medoxomil as it is a category D pregnancy drug and may harm the baby. Do not use Hydrochlorothiazide+olmesartan Medoxomil if you cannot urinate, are dehydrated, have low blood pressure (hypotension), and have or have had cardiogenic shock (sudden stopping of blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing table salt (sodium chloride) in your food often helps lower blood pressure.

Uses of Olmesartan Medoxomil+hydrochlorothiazide

Hypertension (high blood pressure)

Medicinal Benefits

Hydrochlorothiazide+olmesartan Medoxomil is primarily used to treat high blood pressure. Hydrochlorothiazide+olmesartan Medoxomil is a combination of two medicines: Olmesartan and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). It is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin and relaxes blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Hydrochlorothiazide (diuretic or water pill); removes extra water and certain electrolytes from the body. Together, both lower fluid overload, and blood pressure, improve blood flow and reduce the future risk of a heart attack.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Olmesartan Medoxomil+hydrochlorothiazide

  • Stuffy nose/sore throat
  • Nausea
  • Upset stomach
  • Headache
  • High level of uric acid
  • Diarrhoea
  • Electrolyte imbalance
  • Dehydration
  • Dizziness
  • Decreased blood pressure

 

Patients Concern

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force our heart uses to pump blood to all body parts. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

FAQs

Hydrochlorothiazide+olmesartan Medoxomil is a combination of two medicines: Olmesartan medoximil and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). It is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Hydrochlorothiazide+olmesartan Medoxomil lowers the fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Yes, Hydrochlorothiazide+olmesartan Medoxomil can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Hydrochlorothiazide+olmesartan Medoxomil. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

It's unlikely that Hydrochlorothiazide+olmesartan Medoxomil affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.

In case you have missed a dose of Hydrochlorothiazide+olmesartan Medoxomil, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both doses together. Take only one dose; taking a double dose of Hydrochlorothiazide+olmesartan Medoxomil will lead to low blood pressure.

Hydrochlorothiazide+olmesartan Medoxomil can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Hydrochlorothiazide+olmesartan Medoxomil may lead to increased blood pressure with a high risk of heart attack and stroke in future.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

Please inform your doctor before surgery if you are taking Hydrochlorothiazide+olmesartan Medoxomil as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.

Do not use Hydrochlorothiazide+olmesartan Medoxomil if you are pregnant, planning for pregnancy, or unable to urinate. If you have diabetes and taking Hydrochlorothiazide+olmesartan Medoxomil with other blood pressure-lowering pills like 'aliskiren' immediately stop taking both together and consult a doctor.

Available Medicines for

Olmesartan Medoxomil+hydrochlorothiazide

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